Arjunolic acid is one such novel phytomedicine with multifunctional therapeutic applications. It is a triterpenoid saponin, isolated earlier from. This review highlights the beneficial role of arjunolic acid, a naturally occurring chiral triterpenoid saponin, in various organ pathophysiology and the underlying . Abstract. Arjunolic acid, the major extractable constituent of the heavy wood of Ter- minalia Arjuna, has the potential to be used as a rigid and functional.
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The scientific basis for the use of arjunolic acid as cardiotonic in Ayurvedic medicine is proven by its vibrant functions such as prevention of arjunklic necrosis, platelet aggregation and coagulation and lowering of blood pressure, heart rate and cholesterol levels. Lipids and lipid-like molecules. Please upgrade your browser to a newer version to get the best experience on Human Metabolome Database.
A molecular entity capable of donating a hydron to an acceptor Arjunoliic o nsted base. Arjunolic acid, also known as arjunolate, belongs to the class of organic compounds known as triterpenoids.
Property Value Reference Melting Point. Your source for quantitative metabolomics technologies and bioinformatics. These include the extract from the plant Terminalia arjuna srjunolic is a popular cardioprotectant and may prevent or slow progression of pathological hypertrophy to heart failure.
Articles by Sarkar, S. Related Content Load related web page information. Any intermediate or product resulting from metabolism. Adipose tissue function and plasticity orchestrate nutritional adaptation.
Arjunolic acid | C30H48O5 – PubChem
You’ll be in good company. Bronsted acid A molecular entity capable of donating a hydron to an acceptor Br o nsted base. Phytochemicals have gained attention as alternative therapeutics for managing cardiovascular diseases. Its arjunilic multifunctionality is shown by its wound healing, antimutagenic and antimicrobial activity. Services Email ackd article to a friend Alert me when this article is cited Alert me if a correction is posted Alert me when eletters are published Similar articles in this journal Similar articles in PubMed Download to citation manager Request Permissions.
Additives, flavors, and ingredients. EC1 assisted in most experiments with animals. An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. Submit your work to JBC.
A C 30 terpene. Full view Show me all the nodes in this graph. Graph compression Simplified view Show me the possible minimal nodes in this graph. Outside of the human body, arjunolic acid can be found in fruits and guava. Its antioxidant property combined with metal chelating property protects organs from metal and drug induced toxicity. Esters of ajunolic acid function as gelators of a wide variety of organic liquids.
VT4 did extraction and purification of arjunolic acid used in the study. SS1 conceived the idea of the project. The term ‘metabolite’ subsumes the classes commonly known as primary and secondary metabolites. Isolated from Symplocos lancifolia and Juglans sinensisit exhibits antioxidant and antimicrobial activities. Though the beneficial role of this triterpenoid has been assessed from various angles, a comprehensive review of its effects on biochemistry and organ pathophysiology is lacking and this forms the rationale of this review.
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. Lipid rafts and signal transduction.
Simons K, Toomre D: Cardiac hypertrophy and associated heart fibrosis remain a major cause of death worldwide.
Within the cell, arjunolic acid is primarily located in the membrane predicted from logP and cytoplasm. Epub Aug Search for related content. Epub Mar You are using an unsupported browser. Child entities Include all the children relationships for this entity. This compound belongs to the class of organic compounds known as triterpenoids.
Apart from its pathophysiological functions, it possesses dynamic insecticidal property and it is used as a structural molecular framework in supramolecular chemistry and nanoscience. Quantitative metabolomics services for biomarker discovery and validation.
Showing metabocard for Arjunolic acid (HMDB0034502)
AR3 conducted protein modeling and protein-protein docking and analysed the data with SS3. Arjunolic acid is a potent antioxidant and free radical scavenger.
It also plays an effective role in arjunlic protection against both type I and type II diabetes and also ameliorates diabetic renal dysfunctions. Arjunolic acid exists as a solid and is considered to be practically insoluble in water and relatively neutral. Responses Submit a Letter to the Editor. Personalised view Accid your own personalised ontology view, if you wish to remove any entity from your future visualisations please right click the entity e.
TB1 designed and conducted most of the experiments, analyzed the results and wrote the paper with SS1. Property Value Source Water Solubility.